Since the birth of Elizabeth Carr, the first US IVF birth in December 1981, there have been major advancements in ART, and the physicians from RMANJ have provided significant and seminal contributions to improving care and success rates over that time.

RMANJ’s commitment to advancement in ART is demonstrated in more than 200 scientific papers and peer-reviewed articles published in just the last several years.  RMANJ has been nominated for the general program prize paper at the American Society for Reproductive Medicine Meeting (ASRM) four times in the last six years, and won the honor twice – in 2007 and 2010. Members of the RMANJ team have won prize papers seven times – an unparalleled achievement.

In 2012 the team at RMANJ presented interim results of the BEST (Blastocyst Euploid Selective Transfer) Trial, a groundbreaking IVF study which demonstrated uncompromising success rates with single embryo transfer when comprehensive chromosomal screening was used. It also helped reduce the complications associated with multiple twin deliveries, often a result of IVF treatment. The team continues to strive for improved efficacy and safety in IVF treatment across a number of areas including:

  • Embryology
  • Molecular Genetics
  • Transcriptomics
  • Genomics

Recent Research

Below is a list of helpful resources published by RMANJ physicians. Simply click on the title of the article to view the PDF.

In vitro fertilization with single euploid blastocyst transfer: a randomized controlled trial
– Forman EJ; Hong KS; Ferry KM; Tao X; Taylor D; Levy B; Treff NR; Scott RT Jr.  In vitro fertilization with single euploid blastocyst transfer: a randomized controlled trial.  Fertility & Sterility. July 2013; 100(1):100-107.

Single embryo transfer with comprehensive chromosome screening results in improved ongoing pregnancy rates and decreased miscarriage rates.
– Forman EJ; Tao X; Ferry KM; Taylor D; Treff NR; Scott RT Jr.  Single embryo transfer with comprehensive chromosome screening results in improved ongoing pregnancy rates and decreased miscarriage ratesHuman Reproduction. April 2012; 27(4):1217-22.

 

Tracking embryo implantation using cell-free fetal DNA enriched from maternal circulation at 9 weeks gestation.
– Treff  NR, Tao X,  Su J, Lonzcak A., Northrop L.,  A. Ruiz, Scott RT.   Tracking embryo implantation using cell-free fetal DNA enriched from maternal circulation at 9 weeks gestationMol. Hum. Reprod. July 2011; 17(7):434-438.

 

Single-cell whole-genome amplification technique impacts the accuracy of SNP microarray-based genotyping and copy number analyses.
– Treff NR, Su J, Tao X, Northrop L., Scott RT.  Single Cell Whole Genome Amplification Technique Impacts the Accuracy of SNP Microarray Based Genotyping and Copy Number Analyses. Mol. Hum. Reprod. June 2011; 17(6 ): 335–343.

 

SNP microarray-based 24 chromosome aneuploidy screening is significantly more consistent than FISH.
– Treff  NR, Levy B., Su J. ,Northrop L., Tao X, Scott RT.  SNP microarray based 24 chromosome aneuploidy screening is significantly more consistent than FISH. Mol. Hum. Reprod. Aug 2010; 16(8):583-9.

 

SNP microarray-based 24 chromosome aneuploidy screening demonstrates that cleavage-stage FISH poorly predicts aneuploidy in embryos that develop to morphologically normal blastocysts.
– Northrop L., Treff  NR, Levy B., Scott RT.  SNP microarray based 24 chromosome aneuploidy screening demonstrates that   cleavage stage FISH poorly predicts aneuploidy in embryos that develop to morphologically normal blastocysts.  Mol. Hum. Reprod. Aug 2010; 16(8):590-600.