Indications for Treatment: In women who do not ovulate on their own, these drugs induce ovulation, thus the term Ovulation Induction. In women who do ovulate on their own, these drugs are used to produce more follicles from the ovaries in a controlled fashion, thus the expression Controlled Ovarian Hyperstimulation (COH). Gonadotropins are a first line drug for anovulatory women with normal to low FSH and LH levels. They are a second line drug for women who fail to ovulate or conceive after optimal clomiphene citrate (and/or metformin) therapy. They may also be a first or second line drug for ovulatory women with unexplained infertility and endometriosis. In most women, any of the six FSH-containing gonadotropins may be appropriate to use. However, in certain situations, one drug may be more advantageous to you. The choice of medicines will be discussed at your counseling session prior to initiating therapy.