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SUMMIT-SEQUENTIAL VS. MONOPHASIC MEDIA IMPACT TRIAL

Techniques to improve pregnancy and delivery rates in in vitro fertilization (IVF) cycles have focused on conditions in the laboratory that affect ultimate outcome.  The optimal environment for embryo growth in the IVF laboratory has been studied, but no general agreement exists on the best media to use for blastocyst culture (day 5 or day 6 embryos).  Prior studies have shown that culturing embryos in single-step v.s multi-step media have the same outcomes.  Both types of media are commercially available and FDA approved for clinical use.  This study seeks to evaluate these two media with as regard to pregnancy outcome.

INCLUSION CRITERIA

  • Undergoing IVF/CCS
  • Patient meets ASRM guidelines for Double Embryo Transfer (DET)
  • Use of donor sperm is ok
  • Appropriate hormone levels approved by study parameters
  • Patients less than 35 years of age must have had 1 prior failed IVF cycle
  • Patients 35 years of age or greater must have a maximum of 1 prior failed IVF cycle

EXCLUSION CRITERIA

  • Chronic endometrial insufficiency
  • Use of donor egg or gestational carriers
  • Medical contraindications to Double Embryo Transfer
  • Male Factor
  • Communicating hydrosalpinx
  • Single gene disorder or sex selection

DISCOUNT

  • Genetic screening of embryos is free of charge with participation in study.