Well validated and evidence-based treatments are critical when faced with infertility
Proven infertility treatments based on science and evidence is critical to safety and success
Since 1999 RMANJ has been leading the way helping hopeful patients become parents
Your RMANJ care team will help you navigate the many steps in your care
RMANJ blends scientific expertise and innovation with patient-centered care and compassion
Being well informed and having the resources can make all the difference
ARE YOU UNDER 35 YEARS OF AGE & HAVE BEEN TRYING TO GET PREGNANT FOR ONE YEAR WITHOUT SUCCESS?
DID YOU KNOW?
At birth, a woman will have all the eggs she will ever have in her lifetime, nearly 1-million. But by the time she’s in her early 30’s her pool of eggs has decreased substantially to less than half. A secondary challenge for women is one of egg quality: by the time a women is in her late 30’s nearly 40% of her eggs will be of low-quality due to genetic imbalances or other issues related to age.
ARE YOU OVER 35 YEARS OF AGE & HAVE BEEN TRYING TO GET PREGNANT FOR SIX MONTHS WITHOUT SUCCESS?
As a woman enters her late 30’s and early 40’s, the majority of her ovulated eggs are often unable to properly manage their chromosomes (genetic material). As a result, when these eggs fertilize, they are likely to result in embryos that contain chromosomal abnormalities (aneuploidy). Comprehensive Chromosome Screening (CCS) can help patients improve their chances of having a healthy baby.
HAVE YOU EXPERIENCED TWO OR MORE CONSECUTIVE MISCARRIAGES?
Experiencing a miscarriage is a tremendous shock and can leave you with deep-rooted feelings of loss and sorrow.
Approximately 20% of all pregnancies end in miscarriage, most occurring within the first 12 weeks. Recurrent miscarriage can be defined as two or more consecutive losses. When miscarriage occurs this frequently, there may be an underlying cause such as aneuploidy or an imbalance of chromosomes in the genetic makeup of the embryo. Studies suggest that 50-70% of all miscarriages are due to embryos with too few or too many chromosomes, while the risk of aneuploidy increases with a woman’s age.
DO YOU HAVE BLOCKED OR MISSING FALLOPIAN TUBES?
One of the many causes of infertility is tubal disease, in which your fallopian tubes become blocked or damaged. Scar tissue resulting from endometriosis or abdominal or gynecological surgery (bowel surgery, cesarean section, ruptured appendix, etc.) can block the egg from entering or traveling down your fallopian tube to meet the sperm.
HAVE YOU HAD YOUR HORMONES TESTED RESULTING IN ABNORMAL HORMONAL LEVELS?
Hormones control every step in achieving pregnancy-from stimulating the development of an egg to ovulation and implantation of a fertilized egg in the uterus. Each hormone that plays a role in conception must be produced in a specific amount at a precise time in your menstrual cycle. Hormonal studies measure the levels of certain hormones produced by your body during your cycle and help identify hormonal imbalances that may impair your fertility.
High levels of FSH (Follicle Stimulating Hormone) are a common clue of infertility. AMH, or anti-mullerian hormone is a substance produced by granulosa cells in ovarian follicles and has become an important indicator of ovarian reserve for many patients.
DO YOU HAVE IRREGULAR OR SEVERELY PAINFUL MENSTRUAL CYCLES?
Irregular or abnormal ovulation accounts for 30% to 40% of all cases of infertility. Having irregular periods, no periods, or abnormal bleeding often indicates that you aren’t ovulating, a condition known clinically as anovulation. Severely painful menstrual cycles, especially in the lower abdomen or pelvis, or the lower back may by an indication of endometriosis. Both anovulation and endometriosis affect a woman’s reproductive organs which may impair her fertility.
HAS YOUR PARTNER HAD A SEMEN ANALYSIS RESULTING IN LOW OR AN ABNORMAL SPERM COUNT?
Although not a comprehensive measure of fertility, the semen analysis, if abnormal, may suggest that the probability of achieving fertility is statistically low. Among the numbers on the test, the sperm concentration and motility appear to correlate best with fertility. Two well-performed semen analyses can often suggest a diagnosis or direction
DO YOU HAVE A FAMILY HISTORY OF EARLY MENOPAUSE?
Menopause usually occurs in women between the ages of 42 and 56. Premature ovarian failure (early menopause) is a condition in which menopause occurs before the age of 40. Women who develop early menopause usually have run out of eggs in their ovaries. The cause of premature ovarian failure is generally unknown. However, there are a few reasons why the ovaries may stop producing eggs at an early age. Heredity can play a role-some genetic disorders lead to early menopause.
HAVE YOU BEEN DIAGNOSED WITH A LOW EGG SUPPLY?
The term “ovarian reserve” refers to a woman’s current supply of eggs, and is closely associated with reproductive potential. As a woman ages, her supply of eggs gradually declines over time until the eggs are depleted at menopause. Although we expect the ovary to age in a certain way, there are times when it doesn’t behave as predicted. In general, the greater the number of remaining eggs, the better the chance for conception.
HAVE YOU OR YOUR PARTNER HAD A PERSONAL HISTORY OF CHEMOTHERAPY?
Exposure to certain chemicals or medical treatments like chemotherapy and radiation therapy can damage or destroy the ovaries and testis. For women, chemo can damage the ovary and reduce the amount of hormones they produce. Chemotherapy’s effect on men may lower the number of sperm cells, reduce their ability to move, or cause other changes.
Chemotherapy can, but doesn’t always affect sexual organs and how they work. The possible side effects depend on the drugs used, your age, and your overall health. Speak to a fertility specialist to understand your fertility potential.
DO YOU OR YOUR PARTNER HAVE A FAMILY HISTORY OF GENETIC DISEASES?
Humans have 23 pairs of chromosomes in each cell – one derived from mom and one from dad. Genetic disease is caused by abnormalities of gene function. Single gene abnormalities (mutations) are caused by changes in the DNA sequence of a gene. Single gene disorders usually show a characteristic family history of a specific genetic disease. For example, Cystic Fibrosis (CF) is a serious inherited condition that primarily affects the lungs of CF patients.
HAVE YOU TRIED TO GET PREGNANT USING CLOMID & WERE UNSUCCESSFUL AFTER THREE CYCLES?
Clomid does not directly stimulate the ovaries. Rather, Clomid facilitates ovulation by excreting its effects at the hypothalamus, the gland that signals the pituitary to produce FSH, LH, and estrogen. FSH products stimulate the ovaries directly and the response is dose related.
Clomid is known to be effective usually within the first 3 cycles. Studies show that extended Clomid therapy beyond 3 cycles is less likely to be successful and may have adverse effects on the endometrium.
YOU ANSWERED YES TO ONE OR MORE QUESTIONS
The causes of infertility are equally split between men and women in the US. Approximately one third (30%) of the time infertility can be related to male factors such as low sperm count. Another third (30%) can be related to the female, typically an egg quality or egg quantity factor. In about 20% of cases infertility is unexplained, and the remaining infertility can be attributed to a combination of factors in both partners.
If you’ve answered yes to one or more questions on Check My Fertility.com quiz, it might be time to have a conversation with a fertility specialist.
LEARN ABOUT YOUR FERTILITY POTENTIAL
BY CALLING US TODAY 973-656-2089
OR VISITING US AT WWW.RMANJ.COM
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